• Biomarkers Discovery: The Benefit of the Study Exosomes Originated from Merkel Cell Carcinoma Cell Lines 

      Konstantinell, Aelita Gloria Virginia (Doctoral thesis; Doktorgradsavhandling, 2019-08-30)
      Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine form of skin cancer with a rising incidence and a high mortality rate. The risk of developing Merkel cell carcinoma increased among a large number of immunosuppressed patients. The origin of cancer not known and the pathogenesis of MCC not fully understood. Two causes can initiate MCC tumorigenesis, such as accumulation of UV-induced ...
    • Cancer Research 

      Konstantinell, Aelita Gloria Virginia (Journal article; Tidsskriftartikkel, 2017)
      American Association for Cancer Research was founded in 1907 by a group of 11 physicians and scientists interested in cancer research in the Washington, DC. Today, the AACR is the largest professional organization in the world with a membership of 37 000 researchers from 108 countries. This year, AAR Annual Meeting was organized from the 1th to 5th of April in the birthplace of the organization. I ...
    • MicroRNAs as potential biomarkers in Merkel cell carcinoma 

      Konstantinell, Aelita Gloria Virginia; Coucheron, Dag H; Sveinbjørnsson, Baldur; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-26)
      Merkel cell carcinoma (MCC) is a rare and aggressive type of skin cancer associated with a poor prognosis. This carcinoma was named after its presumed cell of origin, the Merkel cell, which is a mechanoreceptor cell located in the basal epidermal layer of the skin. Merkel cell polyomavirus seems to be the major causal factor for MCC because approximately 80% of all MCCs are positive for viral DNAs. ...